New antiepileptic drug trials in developing countries: are they necessary?

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چکیده

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New antiepileptic drug trials in developing countries: are they necessary?

In recent times, antiepileptic drug (AED) development has expanded with at least seven new AEDs being marketed in a variety of countries. However, in this same period there have been very few trials of new AEDs in the developing world where the majority of people with epilepsy reside. There are many problems with the extrapolation of results from AED trials in developed countries, thus underlin...

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The trials of antiepileptic drug trials

Studies of new antiepileptic drugs (AED) present challenges unique to the treatment of seizures and epilepsy. Perhaps the most prominent of these challenges is the ethical concern of using an unproven medication alone in a study of patients with diagnosed epilepsy. As a result, the focus in the design of current methods of evaluating AED has been on patient safety. Given the constraints of the ...

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Trials in developing countries.

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ژورنال

عنوان ژورنال: Seizure

سال: 1996

ISSN: 1059-1311

DOI: 10.1016/s1059-1311(96)80030-6